Co-founded by a
Bioengineering Pioneer
Dr. Molly Shoichet is internationally renowned for her innovative biomaterials and therapeutic delivery strategies. Shoichet addresses critical questions in medicine with her multidisciplinary research approach that spans drug discovery to drug delivery.
AmacaThera is strategically positioned to develop a pipeline of products that build on cutting-edge inventions in injectable hydrogels, formulation design, drug delivery, affinity release and cell therapy.
For more information about publications related to AmacaThera's technology, please visit the Shoichet Lab.
AmacaGel Platform
2010-10-02T00:00:00.000Z • Biomaterials
Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury
M. Douglas Baumann, Catherine E. Kang, Charles H. Tator, Molly S. Shoichet
Published in Biomaterials, Oct. 2010
2006-01-03T00:00:00.000Z • Biomaterials
Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord.
Dimpy Gupta, Charles H. Tator, Molly S Shoichet
Published in Biomaterials, Jan. 2006
2019-03-01T00:00:00.000Z • Brain Research Bulletin
A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system
M. T. Ho, C. J. Teal, Molly S. Shoichet
Published in Brain Research Bulletin, Mar. 2019
Biologics and Cell
2011-12-16T00:00:00.000Z • Biomaterials
Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury
Yuanfei Wang, Michael J. Cooke, Cindi M. Morshead, Molly S. Shoichet
Published in Biomaterials, Dec. 2011
2019-03-01T00:00:00.000Z • Journal of Controlled Release
Controlled release strategy designed for intravitreal protein delivery to the retina
Vianney Delplace, Arturo Ortin-Martinez, En Leh S. Tsai, Alan N. Amin, Valerie Wallace, Molly S. Shoichet
Published in Journal of Controlled Release, Jun. 2019
2020-10-14T00:00:00.000Z • Nature Communications
Biodegradable transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration
Nikolaos Mitrousis, Sabiha Hacibekiroglu, Margaret T. Ho, Yves Sauvé, Andras Nagy, Derek van der Kooy, Molly S. Shoichet
Published in Nature Communications
2016-05-13T00:00:00.000Z • Science Advances
Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles
Malgosia M. Pakulska, Irja Elliott Donaghue, Jaclyn M. Obermeyer, Anup Tuladhar, Christopher K. McLaughlin, Tyler N. Shendruk and Molly S. Shoichet
Published in Science Advances, May 2016
2019-02-02T00:00:00.000Z • Biomaterials
Initial cell maturity changes following transplantation in a hyaluronate-based hydrogel and injected therapeutically in an animal model of stroke
Samantha L. Payne, Anup Tuladhar, Jaclyn M. Obermeyer, Balazs V. Varga, Carter J. Teal, Cindi M. Morshead, Andras Nagy, Molly S. Shoichet
Published in Biomaterials, Feb. 2019
2015-06-10T00:00:00.000Z • Stem Cell Reports
A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation
Brian G. Ballios, Michael J. Cooke, Laura Donaldson, Brenda L. K. Coles, Cindi M. Morshead, Derek van der Kooy, Molly S. Shoichet
Published in Stem Cell Reports, Jun. 2015
2013-11-14T00:00:00.000Z • Journal of Controlled Release
Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke
Yuanfei Wang, Michael J. Cooke, Nadia Sachewsky, Cindi M. Morshead, Molly S. Shoichet
Published in Journal of Controlled Release, Nov. 2013
2012-01-01T00:00:00.000Z • Journal of the American Chemical Society
Tunable growth factor delivery from injectable hydrogels for tissue engineering
Katarina Vulic, Molly S. Shoichet
Published in Journal of the American Chemical Society, Jan. 2012
Small Molecules
2013-03-23T00:00:00.000Z • Journal of Controlled Release
A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.
Matthew J. Caicco, Michael J. Cooke, Yuanfei Wang, Anup Tuladhar, Cindi M. Morshead, Molly S. Shoichet
Published in Journal of Controlled Release, Mar. 2013
2009-12-17T00:00:00.000Z • Journal of Controlled Release
Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel.
Yuanfei Wang, Yakov Lapitsky, Catherine E. Kang, Molly S. Shoichet
Published in Journal of Controlled Release, Dec. 2009
2015-10-14T00:00:00.000Z • Journal of Controlled Release
Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.
Anup Tuladhar, Cindi M. Morshead, Molly S. Shoichet
Published in Journal of Controlled Release, Oct. 2015